A team of scientists from the USA recently highlighted the importance of a third booster dose of Pfizer’s coronavirus vaccine in achieving additional protection against the coronavirus, according to the study published on the preprint website. medRxiv *.
According to a report by News Medical, the majority of available vaccines, including vaccines based on mRNA Developed by the company Pfizer / BioNTech And Modern Follow a two-dose regimen given by intramuscular injection at a specified time interval.
In the current study, scientists examined the effectiveness of a third booster dose of Pfizer in comparison to the original two-dose regimen. In addition, they collected all information about the vaccine.
Pfizer booster dose
Specifically, they assessed the marginal benefit of the third dose using two complementary approaches: a test-negative design and a matching case-control design. The case-negative design includes individuals with a positive COVID-19 test result as ‘cases’ and individuals with a negative test result as ‘controls’. .
In the matched case-control design, “cases” were defined as individuals who tested positive for MERS after the start of the third-dose vaccination programs on August 1, 2021. These individuals had no laboratory-confirmed history of MERS-CoV infection and received at least two doses of the vaccine. In this design, identical controls were selected from the entire community.
Among the individuals who received two doses of the vaccine and were tested for MERS-CoV, about 5.6% showed a positive test result, in contrast, only 3.6% of individuals who received the third booster dose tested positive for MERS-CoV.
The study revealed that the third booster dose of the vaccine BNT162b2 Provides additional protection against corona infection. Moreover, the level of protection offered by the third dose gradually increases over time, reaching the highest level after about two weeks of taking it.
Since the booster vaccination program was only recently introduced, the study was unable to provide the long-term efficacy of the third vaccine dose. Furthermore, the efficacy of the third dose against . has not been addressed COVID-19 intense study.
Overall, the study highlights the importance of a third dose of the vaccine in the face of weakened vaccine immunity.