Seattle Seahawks star DK Metcalf ran 10.37 seconds in the 100m at the Golden Games but failed to make the final.
“These are world-class athletes, very different than football,” said Metcalf, who missed out on a place at next month’s US Olympic trials.
American Cravon Gillespie won the 100m final in 9.96 in Walnut, California.
Great Britain’s CJ Ujah was fourth in 10.03 as he clocked the Olympic qualifying standard with his fastest time in the event since 2017.