People who are particularly sensitive to stress hormones also show signs that they are more likely to develop cardiovascular disease, according to research presented at the 59th Annual Meeting of the European Society of Pediatric Endocrinology..
According to a report by the site time now news The study aims to create a test that can differentiate between people with stress hormones and those with allergies, to help clinicians better determine therapeutic outcomes and reduce adverse effects in those who need treatment with glucocorticoids. .
Interestingly, the protein profile associated with glucocorticoid sensitivity included markers of increased risk for stress-related disorders such as stroke and heart attack and may indicate new possibilities for diagnosis or treatment in these areas..
Glucocorticoids (GCs) Cortisol is a group of hormones produced naturally in the body, one of which is the stress hormone cortisol, which is essential for healthy metabolism and immune function, acting as anti-inflammatory and routinely used to treat allergies, asthma, and other conditions that involve an overactive immune system. different for these hormones.
A test that distinguishes between susceptible and resistant people will be very useful in improving treatment results. The proteins in our bodies are responsible for recognizing, transporting and influencing the actions of hormones such as GCs Therefore, the protein profiles of sensitive and resistant subjects may indicate the efficacy of glucocorticoids.
Chronic stress has long been associated with an increased risk of heart disease and stroke, but the underlying physiological changes are not well understood..
In this study, Dr. Nicholas Nicolaides and colleagues in Athens, Greece investigated whether a set of proteins could be identified that would distinguish between sensitive and resistant people to glucocorticoids. This study was part of a larger project, involving genetic and metabolic analyzes in healthy people with differences in Tissue sensitivity to glucocorticoids.
The team now plans to conduct larger studies to confirm these findings and develop a distinct profile to identify these patient groups, which may also increase susceptibility to stress-related disorders..