Bowel cancer is a general term for cancer cells that multiply uncontrollably in the large intestine (colon and rectum), if not caught early.
And because bowel cancer symptoms can be subtle and not necessarily make you sick, they usually aren’t detected until you develop.
Scientists warn that the presence of a certain type of bacteria in the intestine may increase the risk of developing bowel cancer by 2 to 15%.
Bowel cancer affects more than a quarter of a million people every year, and in industrialized countries, the lifetime risk of developing the disease is about 5%.
When the disease is localized or confined, the cure rate can range from 70% to 90%, however advanced bowel cancer has a high mortality rate and is consistently categorized as the top three causes of cancer-related death worldwide.
A person’s gut is a microbial ecosystem that is densely populated, and if they contain certain bacteria they can increase a person’s risk of developing a fatal disease.
Studies indicate that infection from a common type of oral bacteria can contribute to bowel cancer.
The bacteria, dubbed “Fusobacterium nucleatum”, can attach to colon cells and lead to a series of changes that can lead to bowel cancer, according to the team at Case Western Reserve University’s School of Dentistry.
Scientists have found a way to prevent bacteria from attaching to colon cells. “This discovery creates potential for new diagnostic tools and treatments for cancer treatment and prevention,” lead researcher Yiping Han said in a university press release.
Han, a professor of periodontal disease, added that the results show the importance of good oral health. And in a study published in the US National Library of Medicine National Institutes of Health, further research was done on microorganisms, microbes, and colon cancer.
The study indicated that the human colon is also an anatomical site with the largest number of microbes. It is therefore natural to expect the role of microbes, especially bacteria, in colon and rectal carcinogenesis.
The researchers said: “There has been a long-standing curiosity about the role of bacteria in colon and rectal carcinogenesis, due to the high disease burden of colorectal cancer and the colon microbial load.”
Diets high in saturated fats increase bile acid production, and several studies have identified the association between diets high in saturated fats and colorectal cancer.
Gut bacteria are important factors in bile acid metabolism, and thus may play a role in the biology linking bile acids to bowel cancer, according to the researchers.
In another study published on the “Science Daily” website, colon cancer caused by bacteria and cellular tension was analyzed.
Professor Dirk Haller from the Department of Nutrition and Immunology at the Weihenstephan Science Center of the TUM explained: “Through our study we originally wanted to study the role of bacteria in the intestine in the development of enteritis, but the surprising result for us was the discovery that bacteria with stress in cells cause tumors ( Exclusively in the colon) and without involvement in inflammation. “
He added, “In some patients, ATF6 can act as a diagnostic marker for increased colon cancer risk, and it can indicate the start of treatment at an early stage.”
He continued: “Microbial treatment can be imagined, when we know more about the formation of the bacterial flora. But what has become clear now is that chronic inflammation has no effect on the development of cancer in the colon.”
The American Cancer Society said that diets containing lots of vegetables, fruits and whole grains were associated with a reduced risk of colon or rectal cancer.
The association’s website advises: “Reduce your intake of red meat and processed meats, which have been linked to an increased risk of colon and rectal cancer. If you are not physically active, you may have a higher risk of developing colon or rectal cancer. Increasing your activity may help reduce the risk.”